Pharmaceutical Intermediate CAS 36127-17-0 2-Carbomethoxy-3-Tropinone



main-image WhatsApp/Telegram: +86 19955145978 Wickr : salesNik Shijiazhuang Suking Biotechnology Co.,Ltd. Our hot-selling product CAS125541-22-2 1-N-Boc-4-(Phenylamino)piperidine CAS288573-56-8 KS-0037 CAS 79099-07-3 1-Boc-4-Piperidone BMK Oil 20320-59-6 PMK 28578-16-7 CAS 1451-82-7 2-Bromo-4-Methylpropiophenone CAS23056-29-3 N-Phenylpiperidin-4-amine CAS40064-34-4 4-Piperidone Hydrochloride Monohydrate CAS10250-27-8 CAS 94-24-6 Tetracaine CAS137-58-6 lidocaine CAS94-15-5 Larocaine CAS49851-31-2 2-bromo-1-phenylpentan-1–1-one CAS14176-49-9 Tiletamina CAS 94-09-7 Benzocaine CAS16595-80-5 Levamisole Hydrochloride CAS171596-29-5 tadanafil CAS148553-50-8 Pregabalin 2-Carbomethoxytropinone (2-CMT) is a commonly used organic intermediate in the synthesis of cocaine and its analogues. As of at least 1999 no reaction pathway has been discovered that synthesizes cocaine-like compounds without utilizing the reduction of 2-CMT. The structure of cocaine was discovered by Richard Willstätter in 1898 after he synthesized it from 2-carbomethoxytropinone. Although it was originally believed that 2-CMT in nature was ultimately derived from ornithine and acetic acid, subsequent research has indicated other pathways exist for the biosynthesis of 2-CMT. A β-keto ester, 2-CMT exists in equilibrium with its keto–enol tautomer.

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